Research groups

Grupo: Developmental genetics and evolution of carpels and fruits

In our lab we are interested in FRUIT DEVELOPMENT AND EVOLUTION. Our goal is to understand how fruit patterning is established, and what is the molecular basis of the morphological and functional diversity found in Nature.

WHY: Fruits are a major evolutionary acquisition of Angiosperms. Fruits likely evolved to protect the developing seeds and to ensure seed dispersal, and for that, they have adopted a huge morphological and functional diversity, greatly responsible for the evolutive success of flowering plants. In addition, fruits are of major economic importance, representing the edible part of many crops as well as being a source for production of seed, oil and other compounds

CURRENT PROJECTS

The genetics of carpel development in Arabidopsis

Fruit patterning and fruit traits such as form, size or texture, depend in great extent from carpel patterning, the ovule-bearing floral organs. Carpels form the gynoecium, probably the most complex organ in the plant, organized in a structure of functional modules with specific roles. Our long-term goal is to understand how these modules are specified and spatially distributed in the developing gynoecium. We use genetic, molecular and genomic tools to unravel the architecture of the regulatory networks directing these processes in Arabidopsis, the most widely used model plant, trying to understand how hormone signaling, regulatory hierarchies and protein-protein interactions contribute to finally define carpel morphogenesis.

Conservation of genetic models for carpel and fruit patterning in angiosperms

We have initiated a systematic study of the conservation of the genetic networks directing carpel patterning in Arabidopsis in other unrelated angiosperm species (poppies, legumes, solanaceae, rice...). We are also trying to test if variations in conserved genetic networks directing fruit patterning can explain morphological innovations found in some plant families, as for example the curly spiny fruits that originated in the genus Medicago

Transcriptional regulation of life span in monocarpic plants

Most annual plants have mechanisms to ensure that once a certain amount of fruits and seeds have been produced, all aerial meristems coordinately cease grow to optimize resources to the production of seed. We are investigating the genetic mechanisms underlying this coordinated arrest, in particular studying the role of several transcription factors in the process

Staff Researchers

Other Group Members

Temporary Visitors

África Gomariz Fernández -Tesis

Verónica Sánchez Gerschon -Tesis

Ana Alarcia García- Tesis

Alejandro León Flores - Estudiante de Máster

Clara Ortíz - Investigadora visitante de la Universidad de Antioquía, Colombia

  • Clara Ortiz-Ramirez, Marco A. Giraldo, Cristina Ferrandiz, Natalia Pabon Mora (2019)
    Expression and function of the bHLH genes ALCATRAZ and SPATULA in selected Solanaceae species
  • Cristina Ferrandiz (2019)
    Fruit Development: Turning Sticks into Hearts
    Current Biology 29, R337-9
  • Humberto Herrera-Ubaldo, Paulina Lozano-Sotomayor, Ignacio Ezquer, Maurizio di Marzo, Ricardo A Chávez-Montes, Andrea Gómez-Felipe, Jeanneth Pablo-Villa, David Díaz-Ramírez, Patricia Ballester, Cristina Ferrándiz, Martin Sagasser, Lucia Colombo, Nayelli Marsch-Martínez, Stefan de Folter (2019)
    New roles of NO TRANSMITTING TRACT and SEEDSTICK during medial domain development in Arabidopsis fruits
    Development 146:dev172395
  • Edelín Roque, Concepción Gómez-Mena, Cristina Ferrándiz, Jose Pio Beltrán, Luis Cañas (2018)
    Functional genomics and genetic control of flower and fruit development in Medicago truncatula: An overview
    Methods Mol Biol 1822:273-290
  • Vicente Balanzà, Irene Martínez-Fernández, Shusei Sato, Martin F. Yanofsky, Kerstin Kaufmann, Gerco C Angenent, Marian Bemer, Cristina Ferrándiz (2018)
    Genetic control of meristem arrest and life span in Arabidopsis by a FRUITFULL-APETALA2 pathway
    Nature Communications 9 doi:10.1038/s41467-018-03067-5 .
  • Carol Moreau, Julie M. I. Hofer, Morgane Eléouët, Andrey Sinjushin, Mike Ambrose, Kirsten Skøt, Tina Blackmore, Martin Swain, Matthew Hegarty, Vicente Balanzà, Cristina Ferrándiz, T. H. Noel Ellis (2018)
    Identification of Stipules reduced, a leaf morphology gene in pea (Pisum sativum).
    New Phytologist doi.org/10.1111/nph.15286
  • Di Wu, Wanqi Liang, Wanwan Zhu, Minjiao Chen, Cristina Ferrandiz, Rachel A Burton, Ludovico dreni, Dabing Zhang (2018)
    Loss of LOFSEP transcription factor function converts spikelet to leaf-like structures in rice
    Plant Physiology doi:10.1104/pp.17.00704.
  • Marian Bemer, Hilda van Mourik, Jose M Muiño, Cristina Ferrándiz, Kerstin Kaufmann, Gerco C Angenent (2017)
    FRUITFULL controls SAUR10 expression and regulates Arabidopsis growth and architecture
    Journal of Experimental Botany doi:10.1093/jxb/erx184.
  • Stefanie Menezes de Moura, Sinara Artico, Cassio Lima, Sarah Muniz Nardeli, Ana Berbel, Osmundo Brilhante Oliveira-Neto, Maria Fatima Grossi-de-Sa, Cristina Ferrandiz, Francisco Madueño, Marcio Alves-Ferreira (2017)
    Functional characterization of AGAMOUS-subfamily members from cotton during reproductive development and in response to plant hormones
    Plant reproduction doi:10.1007/s00497-017-0297-y
  • Patricia Ballester, Cristina Ferrandiz (2017)
    Shattering fruits: Variations on a dehiscent theme.
    Current Opinion in Plant Biology 35: 68-75
Cristina Ferrándiz (2016)
My Favourite Flowering Image: Makig petals out of leaves
Flowering Newsletter 2016
Cristina Ferrandiz, Francisco Madueño (2015)
Meeting report: Flowers are always a good excuse to meet!
Flowering Highlights Blog (http://floweringhighlights.org/2015/07/29/)
Cristina Ferrandiz (2014)
On gibberellins and life decisions.
Flowering Highlights Blog doi: 10.1093/jxb/erv114
Cristina Ferrándiz (2011)
Fruit structure and diversity
.Encyclopedia of Life Sciences (ELS) John Wiley & Sons, Ltd: Chichester DOI: 10.1002/9780470015902.a0002044.pub2
Expresión y caracterización funcional comparada de genes de desarrollo de fruto en capsulas y bayas de las Solanaceae. COOPB20250
Entidad financiadora: 
CSIC. Program iCOOP+16
IP: 
Cristina Ferrandiz

LongLifeCrop: Understanding the molecular basis of global proliferative arrest in monocarpic plants: biotechnological strategies for increased fruit and seed production in annual crops. DGI BIO2015- 64531-R.

Entidad financiadora: 
MINECO.
IP: 
Cristina Ferrándiz
ExpoSeed: Exploring the molecular control of seed yield in crops. H2020-MSCA-RISE-2015
Entidad financiadora: 
Unión Europea
IP: 
Raffaella Bataglia (CREA, Italy)
RiceStyle: Carpel evolution: a walk in the rice side. H2020-MSCA-IF-2014-661678.
Entidad financiadora: 
Unión Europea
IP: 
Cristina Ferrandiz
FRUITLOOK: The physiology and genetics of fruit formation: from genes to networks. FP7-PEOPLE- PIRSES-2013-612640
Entidad financiadora: 
Unión Europea
IP: 
Simona Masiero (U. Milano, Italy)
LEGATO: Legumes for the agriculture of tomorrow. FP7- KBBE-2013-7-613551
Entidad financiadora: 
Unión Europea
IP: 
Richard Thompson (INRA, France).
Evolutionary Conservation of Regulatory Networks Controlling Flower Development (PIRSES-2009-247589), 01-07-2010/30-06-2014.
Entidad financiadora: 
Unión Europea, programa IRSES.
IP: 
Lucia Colombo/Simona Masiero
CarpelCode: A combinatorial code of transcription factors to regulate carpel and fruit patterning. BIO2012-32902.
Entidad financiadora: 
MINECO
IP: 
Cristina Ferrándiz
Conservation of genetic models for carpel and fruit patterning in Eudicots (BIO2009-09920), 01-10-2009/30-09-2012.
Entidad financiadora: 
MICINN
IP: 
Cristina Ferrandiz
Función y potencial biotecnológico de los factores de transcripción de las plantas (TRANSPLANTA), " Plant Development" team (CSD 2007-00057), 01-01-2007/31-12-2011.
Entidad financiadora: 
Programa Consolider-Ingenio 2010, Ministerio de Ciencia e Innovación
IP: 
Javier Paz-Ares
El papel integrador de los genes TOP y la señalización por auxinas en las rutas de morfogénesis del fruto en Arabidopsis (DGI BIO2006-10358)
Entidad financiadora: 
Ministerio de Educación y Ciencia
IP: 
Cristina Ferrándiz Maestre
La integración de las distintas rutas de morfogénesis del fruto de Arabidopsis mediado por auxinas (DGI BIO2005-01541), 01-12-2005/30-11-2006.
Entidad financiadora: 
Ministerio de Educación y Ciencia
IP: 
Cristina Ferrándiz Maestre
“Grain Legumes: New strategies to improve grain legumes for food and feed” ,
Entidad financiadora: 
Unión Europea
IP: 
Francisco Madueño (subproyecto). Noel Ellis (proyecto integrado).
Análisis funcional del gen MADS box FRUITFULL en el desarrollo de inflorescencias y frutos de Arabidopsis: Uso de nuevos alelos de actividad transcripcional modificada (GV04B-262),
IP: 
Cristina Ferrándiz Maestre
Análisis funcional de factores trancripcionales de la familia B3 de Arabidopsis implicados en el desarrollo del fruto (DGI BIO2002-01301),
Entidad financiadora: 
Ministerio de Ciencia y Tecnología
IP: 
Cristina Ferrándiz Maestre
Título: 
TRANSGENIC PLANTS WITH INCREASED NUMBER OF FRUITS AND SEEDS AND METHOD FOR OBTAINING THEREOF
Fecha de solicitud: 
Tuesday, 31 March, 2015
Referencia ID: 
PCT/EP2015/057086
Autores: 
Cristina Ferrandiz, V Balanzà, I Martínez, F Madueño, A Berbel, C Fourquin, A Serrano.
La ruta FUL-AP2 y la longevidad de los meristemos en Arabidopsis thaliana. Bases moleculares y potencial biotecnológico
Año: 
2017
Nombre: 
Irene Martínez Fernández
Universidad: 
Universidad Politécnica de Valencia, ETSIA
Dirigida por: 
Cristina Ferrándiz Maestre
Tipo: 
Tesis Doctorales
Estudio de los complejos transcripcionales que dirigen la formación del pistilo en angiospermas mediante la identificación de sus dianas moleculares y de su conservación funcional durnate la evolución de las angiospermas
Año: 
2017
Nombre: 
Africa Gomariz Fernández
Universidad: 
Universidad Miguel Hernández de Elche
Dirigida por: 
Cristina Ferrándiz Maestre
Tipo: 
Tesis Doctorales
Identificación De Las Dianas Moleculares De Los Genes NGATHA Y Caracterización De Su Papel En El Desarrollo Del Gineceo Y El Fruto De Arabidopsis thaliana
Año: 
2016
Nombre: 
Patricia Ballester Fuentes
Universidad: 
Universidad Politécnica de Valencia, ETSIA
Dirigida por: 
Cristina Ferrándiz
Tipo: 
Tesis Doctorales
Nuevas Funciones y Dianas Moleculares del Factor de Transcripción FRUITFULL en Arabidopsis thaliana
Año: 
2011
Nombre: 
Vicente Balanzá Pérez
Universidad: 
Universidad Politécnica de Valencia,ETSIA
Dirigida por: 
Cristina Ferrándiz
Tipo: 
Tesis Doctorales
Análisis Funcional de Genes Reguladores del Desarrollo del Fruto y su Relación con las Vías Reguladas por Auxinas.
Año: 
2011
Nombre: 
Maria Luisa Navarrete Gómez
Universidad: 
Universidad Politécnica de Valencia,ETSIA
Dirigida por: 
Cristina Ferrándiz
Tipo: 
Tesis Doctorales
Análisis funcional de factores transcripcionales de la familia B3 de Arabidopsis implicados en el desarrollo del fruto
Año: 
2008
Nombre: 
MarinaTrigueros González
Universidad: 
Universidad Politécnica de Valencia, ETSIA
Dirigida por: 
Cristina Ferrándiz
Tipo: 
Tesis Doctorales